Liquid purification or separation – With means to add treating material – Chromatography
Patent
1982-02-16
1984-04-03
Adee, John
Liquid purification or separation
With means to add treating material
Chromatography
55155, 204290R, 204302, 2101981, 210748, 210205, B01D 1508
Patent
active
044406380
ABSTRACT:
A device capable of manipulating, sorting, separating and measuring the properties of charged species particles by physical interaction via electrostatic forces. The device operates on charged species particles ranging from small molecular species to intact mammalian cells. The device has a semiconductor substrate serving as an electrode. A dielectric layer overlays the substrate. A chamber holds a fluid which contains the charged species particles. The fluid in the chamber is placed in physical contact with the dielectric layer. A control electrode of metal is disposed opposite the dielectric layer and is also in physical contact with the fluid. A voltage source establishes an electric field between the electrodes which extends into the liquid. Charged species particles are either attracted to or repelled from the dielectric layer surface. The device structure readily provides for precise and continuous control of the electric field at the dielectric layer-fluid boundary interface. The electric field can be of either polarity and can be maintained with low levels of current flow.
REFERENCES:
patent: 2364118 (1944-12-01), Wolfe
patent: 4020830 (1977-05-01), Johnson et al.
patent: 4180771 (1977-12-01), Guckel
patent: 4214981 (1980-07-01), Giddings
patent: 4255247 (1981-03-01), Oda et al.
patent: 4358379 (1982-11-01), Inoue
Gingell, D. and J. A. Fornes., Interaction of Red Blood Cells With a Polarized Electrode. Evidence of Long-Range Intermolecular Forces. Biophysical 1976, J. 16:1131.
Gingel, D. & I. Todd; Adhesion of Red Blood Cells to Charged Interfaces Between Imiscible Liquids. A New Method. J. Cell. Sci. 18:227, 1975.
Fay, F. S., P. H. Cooke & P. G. Canaday. Contractile Properties of Isolated Smooth Muscle Cells. in Physiology of Smooth Muscle, E. Bulbring and M. F. Shuba, Eds. Raven Press, New York, 1976.
Bioradiations, No. 31, Aug. 1979. Published by the Chemical Division of Bio-Rad Laboratories. p. 1, Bio-Carriers.
Hannig, K. and H. G. Heidrich. The Use of Continuous Preparative Free-Flow Electrophoresis For Dissociating Cell Fractions and Isolation of Membraneous Components. Meth. Enzymol. 31:746, 1974.
Giddings, J. C., S. R. Fisher and M. N. Myers. Field-Flow Fractionation. One-Phase Chromatography for Macromolecules and Particles. American Laboratory, May, 1978, p. 15.
Jacobson, B. S., Isolation of Plasma Membranes From Eukaryotic Cells in Polylysinecoated Polyacrylamide Beads. Biochem. Biophys. Acta. 471:331, 1977.
Kinoshita, T., R. L. Nachman and R. Minick. Isolation of Human Platelet Plasma Membranes With Polylysine Beads. J. Cell. Biol. 82:688, 1979.
Bioradiations, No. 31, p. 3, Affi-Gel 731-Isolates Cell Membranes. Published By the Chemical Division of Bio-Rad Laboratories.
Kaiser, N., Laser Absorption Spectroscopy With An ATR Prism. IEEE Transact. Biomed. Engn. 26:597, 1979.
Todd, I. and D. Gingell. Red Blood Cell Adhesion. I. Determination of the Ionic Conditions For Adhesion to an Oil-Water Interface. J. Cell. Sci. 41:125, 1980.
Gingell, D. and I. Todd., Red Blood Cell Adhesion. II. Interferometric Examination of the Interaction With Hydrocarbon, Oil and Glass. J. Cell. Sci. 41:135, 1980.
Parsegian, V. A. and D. Gingell. Red Blood Cell Adhesion. III. Analysis of Forces. J. Cell. Sci. 41:151, 1980.
Judy Millard M.
Sutko John L.
Adee John
U.T. Board of Regents
LandOfFree
Surface field-effect device for manipulation of charged species does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Surface field-effect device for manipulation of charged species, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Surface field-effect device for manipulation of charged species will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-666196