Surface exposed immunoglobulin D-binding protein from...

Details Surface exposed immunoglobulin D-binding protein from... Surface exposed immunoglobulin D-binding protein from...

2011-07-19

2011-07-19

Graser, Jennifer (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S185100, C424S190100, C424S192100, C435S004000, C435S007320

Reexamination Certificate

active

07981434

ABSTRACT:
The present invention relates to a surface exposed protein, which can be detected inMoraxella catarrhalis, having an amino acid sequence as described in SEQ ID NO: 1, an apparent molecular weight of 200 kDa and a capacity of selectively binding membrane bound or soluble IgD, to an immunogenic or IgD-binding fragment of said surface exposed protein, and to an immunogenic and adhesive fragment of said surface exposed protein. DNA segments, vaccines, plasmids and phages, non human hosts, recombinant DNA molecules and plants, fusion proteins and polypeptides and fusion products are also described. A method of detecting IgD, a method of separating IgD, a method of isolation of a surface exposed protein ofMoraxella catarrhalisand a method for treatment of an autoimmune disease are also disclosed.

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