Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic
Patent
1992-09-11
1994-12-27
Saunders, David
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is inorganic
435968, 436164, 436514, 436524, 436536, 436538, 436541, 436805, G01N 33553
Patent
active
053765567
ABSTRACT:
A method, composition, device, apparatus, and kit for the determination of the presence or amount of an analyte by monitoring an analyte-mediated ligand binding event in a test mixture which contains the analyte to be assayed, a specific binding member, a Raman-active label, and a particulate having a surface capable of inducing a surface-enhanced Raman light scattering. The test mixture is illuminated with a radiation sufficient to cause the Raman-active label in the test mixture to emit a detectable Raman spectrum. The differences in the detected surface-enhanced Raman scattering spectra are dependent upon the amount of the analyte present in the test mixture. Thus, by monitoring these differences, the presence or amount of the analyte are determined.
REFERENCES:
patent: 4094647 (1978-06-01), Deutsch et al.
patent: 4134792 (1979-01-01), Boguslaski et al.
patent: 4186146 (1980-01-01), Butte, Jr. et al.
patent: 4235601 (1980-11-01), Deutsch et al.
patent: 4298688 (1981-11-01), Kallies
patent: 4361537 (1982-11-01), Deutsch et al.
patent: 4366241 (1982-12-01), Tom et al.
patent: 4517288 (1985-05-01), Giegel et al.
patent: 4740468 (1988-04-01), Weng et al.
patent: 4948726 (1990-08-01), Longoria
patent: 5102788 (1992-04-01), Cole
patent: 5266498 (1993-11-01), Tarcha et al.
Rohr et al, "Immunoassay Employing Surface Enhanced Raman Spectroscopy", Analytical Biochemistry, 1989, 182, pp. 388-398.
Hildebrandt et al, "Enhanced Resonance Raman Spectroscopy of Rhodamine 6G Absorbed on Colloidal Silver", J. Physical Chemistry, 1984, 88, 5935-5944.
C. H. Keller et al., "The Abbott IMx.RTM. and IMx SELECT.TM. Systems", J. Clinical Immunoassay, v.14, No. 2, 1991.
M. Fiore et al., "The Abbott IMx.TM. Automated Benchtop Immunochemistry Analyzer System", Clinical Chemistry, V.34, No. 9, 1988.
P. C. Hiemenz, "Principles of Colloid and Surface Chemistry", 1977, pp. 352-491.
D. H. Napper, "Steric Stabilization", J. of Colloid and Interface Science, v. 58, No. 2, 1977.
R. I. Feigen and D. H. Napper, "Depletion Stabilization and Depletion Flocculation", J. Of Colloid and Interface Science, v. 75, No. 2, (1980).
P. K. Aravind, A. Nitzan, and H. Meitu, "The Interaction Between Electromagnetic Resonances And Its Role In Spectroscopic Studies Of Molecules Adsorbed On Colloidal Particles Or Metal Spheres", Surface Science, 110 (1981).
H. Metiu, "Surface Enhanced Spectroscopy", Progress in Surface Science, v. 17 (1984).
R. F. Zuk et al., "Enzyme Immunochromatography-A Quantitative Immunoassay Requiring No Instrumentation", Clinical Chemistry, v.31, No. 7, (1985).
F. Ni et al., "Surface-Enhanced Resonance Raman Study of Avidin-Dye Interactions: A Model for Chromophore-Containing Proteins", J. of Raman Spectroscopy, v. 19, pp. 429-438, 1988.
P. C. Lee et al., "Adsorption and Surface-Enhanced Raman of Dyes on Silver and Gold Sols.sup.1 ", J. Physical Chemistry, v. 86, No. 17, pp. 3391-3395, 1982.
Cotton Therese
Markese James J.
Rohr Thomas E.
Rospendowski Bernard N.
Tarcha Peter J.
Abbott Laboratories
Chin Christopher L.
Saunders David
Schmidt Richard D.
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