Surface enhanced Raman spectroscopic nano-imaging probe and...

Optics: measuring and testing – By dispersed light spectroscopy – With raman type light scattering

Reexamination Certificate

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C385S116000

Reexamination Certificate

active

11186521

ABSTRACT:
Provided herein is a reusable nano-imaging probe useful in surface enhanced Raman spectroscopic (SERS) applications demonstrating nanometer scale resolution. The nano-imaging probe generally comprises a fiber optic imaging bundle of fiber optic elements each having a tapered etched end and a non-tapered non-etched end. The tapered etched ends further comprise a SERS-active metal substrate deposited thereon effective to create a uniform SERS enhancement for an analyte or other substance of interest. Also provided is a SERS nanoimager for dynamic chemical imaging using the nano-imaging probe and methods of imaging and Raman spectral analysis and identification using the nano-imaging probe.

REFERENCES:
patent: 5633972 (1997-05-01), Walt et al.
patent: 7012687 (2006-03-01), Blumberg et al.

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