Chemistry: analytical and immunological testing – Pyrolysis – combustion – or elevated temperature conversion
Patent
1997-01-17
1999-04-13
Alexander, Lyle A.
Chemistry: analytical and immunological testing
Pyrolysis, combustion, or elevated temperature conversion
436173, 436178, 250287, G01N 2175
Patent
active
058940634
ABSTRACT:
This invention relates generally to a mass spectrometer probe and method of using said probe for desorption and ionization of analytes. The sample probe comprises a layer of energy absorbing molecules on the surface of the probe, free of analyte. The analyte is applied to the layer of energy absorbing molecules. The analyte can be desorbed by a high energy source and detected in the mass spectrometer. The probe and methods are useful in detection and analysis of macromolecules such as proteins or other biomolecules.
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Hutchens T. William
Yip Tai-Tung
Alexander Lyle A.
Baylor College of Medicine
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