Surface-enhanced lanthanide chelates

Details Surface-enhanced lanthanide chelates Surface-enhanced lanthanide chelates

2011-03-15

2011-03-15

Yu, Melanie J (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

C436S518000, C436S525000, C435S007100, C435S283100, C435S287100, C435S287200, C422S050000, C422S082050

Reexamination Certificate

active

07906343

ABSTRACT:
A lanthanide chelate is linked to a noble metal substrate at a proximity wherein the substrate enhances a fluorescent emission of the lanthanide by at least 20-fold when the chelate is illuminated at an excitation wavelength that induces a transition in the lanthanide that results in the fluorescent emission.

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Lakowicz et al., Effects of Silver Island Films on the Luminescent Intensity and Decay Times of Lanthanide Chelates, 2002, Jouranl of Fluorescence, vol. 12, pp. 431-437.
Li et al., Amine reactive forms of a luminescent diethylenetriaminepentaacetic acid chelate of Terbium and Europium: Attachment to DNA and Energy Transfer Measurements, 1997, Bioconjugate Chemistry, vol. 8, pp. 127-132.
Lakowicz et al., Effects of Silver Island Films on the Luminescent Intensity and Decay Times of Lanthanide Chelates, Journal of Fluorescence, vol. 12, Nos. 3/4, 2002, pp. 431-437.

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