Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Biocides; animal or insect repellents or attractants
Reexamination Certificate
2005-02-15
2005-02-15
Riley, Jezia (Department: 1637)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Biocides; animal or insect repellents or attractants
C424S426000, C435S006120, C514S001000, C514S04400A
Reexamination Certificate
active
06855329
ABSTRACT:
The invention provides a biodegradable and biocompatible polymer article having a surface wherein a biologically active ligand is provided on said surface in a spatially controlled pattern. The pattern may be formed using a poly(dimethyl siloxane) mold. The biologically active ligand may be attached to the polymer article by a biotin-avidin-biotin linkage.
REFERENCES:
patent: 4282287 (1981-08-01), Giese
patent: 5252743 (1993-10-01), Barrett et al.
patent: WO 9640002 (1996-12-01), None
patent: WO 9707429 (1997-02-01), None
patent: WO 9733737 (1997-09-01), None
Barrera, et al., “Synthesis and RGD peptide modification of a new biodegradable copolymer. Poly(lactic acid co-lysine),”J Am Chem Soc115:11010-11011 (1993).
Cook, et al., “Characterization and development of RGD-peptide-modified poly(actic acid-co-lysine) as an interactive, resorbable biomaterial,”Journal of Biological Materials Research35:513-523 (1997).
Danielsen, “Nerve regeneration and repair,”Diabetic Medicine13:677-678 (1996).
Delamarche, et al., “Patterned delivery of immunoglobulins to surface using microfluidic networks,”Science276:779-81(1997).
Hubbell, “Biomaterials in tissue engineering,”Biotechnol13:565-76 (1995).
Kumar, et al., “Patterning self-assembled monolayers: Applications in materials science,”Langmuir10:1498-1511 (1994).
Langer & Vacanti, “Tissue engineering,”Science260:920-927 (1993).
Langer, “1994 Whitaker Lecture: Polymers for drug delivery and tissue engineering,”Annals of Biomedical Engineering23:101-111 (1995).
Lhoest, et. al., “A new plasma-based method to promote cell adhesion on micrometric tracks on polystyrene substrates,”J Biomater Sci Polymer Edn7(12):1039-1054 (1996).
Mrksich & Whitesides, “Using self-assembled monolayers to understand the interactions of man-made surfaces with proteins and cells,”Annu Rev Biophys Biomol Struct25:55-78 (1996).
Pande, et al., “A biotinylated undecylithiophene copolymer bioconjugate for surface immobilization: Creating an alkaline phosphatase chemiluminescence-based biosensor,”Bioconjugate Chem. 7:159-164 (1996).
Ranieri, et al., “Neuronal cell attachments to fluorinated ethylene propylene films with covalently immobilized laminin oligopeptides YIGSR and IKVAV. II,”Journal of Biomedical Materials Research29:779-785 (1995).
Ranieri, et al., “Spatial control of neuronal cell attachment and differentiation of convalently patterned laminin oligopeptide substrates,”Int J Dev Neuorsci12(8):725-735 (1994).
Schmidt, et al., “Stimulation of neurite outgrowth using an electrically conducting polymer,”Proc Natl Acad Soc USA94:8948-8953 (1997).
Spargo, et al., “Spatially controlled adhesion, spreading, and differentiation of endothelial cells on self-assembled molecular monolayers,”Proc Natl Acad Sci USA91:11070-11074 (1994).
Xia & Whitesides, “Extending microcontact printing as a microlithographic technique,”Langmuir12:2059-67 (1997).
Cannizzaro Scott M.
Langer Robert S.
Patel Nikin
Shakesheff Kevin
Massachusetts Institute of Technology
Pabst Patent Group LLP
Riley Jezia
The University of Nottingham
LandOfFree
Surface coating spatially controlled patterns does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Surface coating spatially controlled patterns, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Surface coating spatially controlled patterns will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3467726