Surface coating comprising bioactive compound

Details Surface coating comprising bioactive compound Surface coating comprising bioactive compound

2003-10-21

2008-12-02

Carlson, Karen Cochrane (Department: 1656)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

Reexamination Certificate

active

07459169

ABSTRACT:
Coatings comprising protein resistant components and therapeutic components on medical devices are disclosed. The coatings act to down-regulate complement activation. Medical devices can be coated with these coatings to prevent side effects and improve patency.

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Andersson et al., Binding of a model regulator of complement activation (RCA) to a biomaterial surface: surface-bound factor H inhibits complement activation, Biomaterials 22 (2001), pp. 2435-2443.

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