Surface-bound fluorescent polymers and related methods of synthe

Details Surface-bound fluorescent polymers and related methods of synthe Surface-bound fluorescent polymers and related methods of synthe

1993-09-07

1994-10-11

Bleutge, John C.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Polymers from only ethylenic monomers or processes of...

526270, 526312, 428500, 128634, 422 681, 436172, 2504611, 25230132, 25230135, 2524081, 252700, C08F22400

Patent

active

053548256

ABSTRACT:
A fiber optic sensing device for measuring a chemical or physiological parameter of a body fluid or tissue is provided. To one end of the fiber is attached a polymer including a plurality of photoactive moieties selected from the group consisting of chromophores and lumophores, the photoactive moieties spaced apart so as to minimize chemical or physical interaction therebetween while optimizing the density of photoactive moieties. In one embodiment, a polymer chain is covalently bound to photoactive moieties through functional groups such as esters, amides, or the like. In a second embodiment, a polymer chain is inherently fluorescent and is formed from at least one monomeric unit. These devices are particularly useful as pH and oxygen sensors.

REFERENCES:
patent: 4803049 (1989-02-01), Hirschfeld et al.
patent: 4812532 (1989-03-01), Stolowitz
patent: 5252494 (1993-10-01), Walt
Munkholm et al. "Polymer Modification of Fiber Optic Chemical Sensors as a Method of Enhancing Fluorescence Signal for pH Measurement" 1986.
Saari et al., Anal. Chem. 54: 821-823 (1982).
Abstract JP 49062589.

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