Surface-bound fluorescent polymers and related methods of synthe

Details Surface-bound fluorescent polymers and related methods of synthe Surface-bound fluorescent polymers and related methods of synthe

1994-05-17

1996-01-02

Sellers, Robert E.

Stock material or miscellaneous articles

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Of quartz or glass

427157, 526268, 526270, 526312, 25230132, 25230135, 2524081, 252700, 428500, B32B 1710

Patent

active

054807239

ABSTRACT:
A fiber optic sensing device for measuring a chemical or physiological parameter of a body fluid or tissue is provided. To one end of the fiber is attached a polymer including a plurality of photoactive moieties selected from the group consisting of chromophores and lumophores, the photoactive moieties spaced apart so as to minimize chemical or physical interaction therebetween while optimizing the density of photoactive moieties. In one embodiment, a polymer chain is covalently bound to photoactive moieties through functional groups such as esters, amides, or the like. In a second embodiment, a polymer chain is inherently fluorescent and is formed from at least one monomeric unit. These devices are particularly useful as pH and oxygen sensors.

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