Suramin and active analogues thereof in the treatment of hyperca

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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A61K 3117

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active

051735091

ABSTRACT:
A method is disclosed for the treatment of hypercalcemia in a patient, by administering to the patient an effective amount of suramin, or an active analogue thereof, for lowering calcium plasma levels in the patient. Human data shows a single course of treatment lowers plasma calcium levels to normal for three months.

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R. Klecker et al., Journal of Liquid Chromatography, 8(9), 1685-1696 (1985).
Stein et al., Journal of Clinical Oncology, vol. 7, No. 4 (Apr. 1989) pp. 499-508.
Jentsch et al., J. of Gen. Virol. (1987), vol. 68, pp. 2183-2192.

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