Suppression of premature labor by use of aromatase inhibitors

Details Suppression of premature labor by use of aromatase inhibitors Suppression of premature labor by use of aromatase inhibitors

1984-04-09

1985-02-19

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

A61K 3156

Patent

active

045005230

ABSTRACT:
This invention relates to the use of aromatase inhibitors to suppress premature labor in mammals by administering an aromatase inhibitor preferably 4-hydroxy-4-androstene-3,17-dione or 4-acetoxy-4-androstene-3,17-dione to a pregnant mammal.

REFERENCES:
patent: 4235893 (1980-11-01), Brodie et al.
Brodie et al., Steroids, 38: 693-702 (1981).
Taylor et al., Journal of Obstetrics and Gynecology, 146, No. 5, pp. 557-567 (Jul. 1983).
Weiss et al., Proceedings of the Society for Experimental Biology and Medicine, 151, pp. 113-116 (1976).
Chemical Abstracts (1979) vol. 91 Par. 168,933 (J).
Chemical Abstracts (1982) vol. 97 Par. 120,724 (P).
Chemical Abstracts (1982) vol. 97 Par. 104,455 (T).

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