Suppression of nuclear factor-κB dependent processes...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C536S023100, C536S024100, C536S024500, C435S006120, C435S375000, C435S377000

Reexamination Certificate

active

07655635

ABSTRACT:
Antisense oligonucleotides which hybridize with nuclear factor-κB (NF-κB) mRNA and methods of using these oligonucleotides.

REFERENCES:
patent: 6069008 (2000-05-01), Bennett et al.
patent: 6207646 (2001-03-01), Krieg et al.
patent: 6239116 (2001-05-01), Krieg et al.
patent: 6653292 (2003-11-01), Krieg et al.
Jen et al., Stem Cells, vol. 18:307-319, 2000.
Agrawal S., TIBTECH vol. 14:376-387, Oct. 1996.
Branch A., TIBS vol. 23:45-50, Feb. 1998.
Baeuerle P.A., “The Inducible Transcription Activator NF-PB: Regulation by Distinct Protein Subunits,”Biochimica et Biophysica Acta, 1072:63-80 (1991).
Branch A.D., “A good antisense molecule is hard to find”,Trends Biochem. Sci., 23(2):45-50 (1998).
Fakler et al., “Short antisense oligonucleotide-mediated inhibition is strongly dependent on oligo length and concentration but almost independent of location of the target sequence”,J. Biol. Chem., 269:16187-16194 (1994).
Ghosh et al., “Cloning of the p50 DNA Binding Subunit of NF-PB: Homology torelanddorsal,” Cell, 62:1019-1029 (1990).
Gibbs W.W., “State of shock. Sepsis can be fatal to firms as well as to patients”Scientific American, 271(4):133-134 (1994).
Kitajima et al, “Human T-cell Leukemia Virus Type I Tax Transformation is Associated with Increased Uptake of Oligodeoxynucleotides in Vitro and in Vivo*,”J. Biol. Chem., 267:25881-25888 (1992).
Libermann et al., “Activation of Interleukin-6 Gene Expression through the NF-PB Transcription Factor,”Molecular Cellular Biology, 10:2327-2334 (1990).
Nolan et al., “DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide,”Cell, 64:961-969 (1991).
Ruben et al., “Isolation of arel-Related Human cDNA That Potentially Encodes the 65-kD Subunit of NF-PB,”Science, 251:1490-1493 (1991).
Staal et al, “Intracellular Thiols Regulate Activation of Nuclear Factor PB and Transcription of Human Immunodeficiency Virus,”Proc. Natl. Acad. Sci.USA, 87:9943-9947 (1990).
Uhlmann et al., “Antisense Oligonucleotides: A New Therapeutic Principle,”Chemical Reviews, 90(4):544-584 (1990).

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