Suppression of non-coupled spins in NMR imaging and spectroscopy

Electricity: measuring and testing – Particle precession resonance – Using a nuclear resonance spectrometer system

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324311, G01R 3320

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active

047060247

ABSTRACT:
A method for suppressing undesired NMR response signals from uncoupled resonances while obtaining desired NMR signals from a sample containing like nuclei which are coupled to one another, precedes each NMR response-signal-evoking excitation signal sequence with a pulse sequence having radio-frequency (RF) pulses providing a 90.degree. rotation of the spin magnetization about a first axis and then providing a 180.degree. degree rotation of the spin magnetization about a second axis, substantially orthogonal to the first axis, in the plane of magnetization rotation, prior to the alternating presence of a second 90.degree. RF pulse causing rotation about the first axis prior to the start of an associated imaging sequence. Time intervals T, of substantially alike duration related to the coupling constant J of the coupled nuclei, occur between each of the pulses; that one of the alternating sequences which is devoid of the second 90.degree. RF pulse has a pair of consecutive time intervals T occurring between the consecutive 180.degree. pulses. The response signal data of a second one of a sequential set is subtracted from the first set of data, to cause suppression of uncoupled resonance response signals. The suppression of water resonance response data obtained by this method is substantially independent of chemical shift, spin-lattice coupling T.sub.1 and spin-spin coupling T.sub.2.

REFERENCES:
patent: 4570119 (1986-02-01), Wehrli et al.
patent: 4583044 (1986-04-01), Case et al.
Dixon, W. T., "Simple Proton Spectroscopic Imaging", Radiology, 1984; 153, pp. 189-194.

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