Suppression of megakaryocytopoiesis by macrophage inflammatory p

Details Suppression of megakaryocytopoiesis by macrophage inflammatory p Suppression of megakaryocytopoiesis by macrophage inflammatory p

1991-11-15

1994-04-26

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 21, A61K 3702

Patent

active

053067096

ABSTRACT:
Macrophage inflammatory protein-1 or -2, or analog thereof, is administered to a mammal to achieve therapeutic reduction of the number of circulating platelets. The proteins are useful in treating essential thrombocythemia and reactive thrombocytosis.

REFERENCES:
patent: 4493795 (1985-01-01), Nestor, Jr. et al.
patent: 4671958 (1987-06-01), Rodwell et al.
Broxmeyer et al., Blood vol. 76, No. 6 (Sep. 15, 1990) 1110-1116.
Graham et al., Letters to Nature vol. 344 (Mar. 1990).
Sherry et al., J. Exp. Med. 186, 2251-2259 (1988).
Zipfel et al., J. Immunol. 142, 1582-1590 (1989).
Irving et al., Nucleic Acids Res. 18, 3261-3270 (1990).
Wolpe et al., Proc. Natl. Acad. Sci. USA 86, 612-616 (1989).
Tekamp-Olson et al., J. Exp. Med. 172, 911-919 (1990).

Affiliated with

Also associated with

Rating

Suppression of megakaryocytopoiesis by macrophage inflammatory p does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Suppression of megakaryocytopoiesis by macrophage inflammatory p, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Suppression of megakaryocytopoiesis by macrophage inflammatory p will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1711880