Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1982-03-08
1989-10-10
Rosen, Sam
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424430, 424436, 514563, 514613, 514617, 514946, 514947, 514966, 514967, 514 2, A61K 902
Patent
active
048730874
ABSTRACT:
A preparation containing an absorption promoter selected from N-acyl amino acid derivatives or N-acyl peptide derivatives represented by the formula: R-CO-A (R is an aliphatic hydrocarbon group, an aromatic hydrocarbon group or an aryl-substituted lower hydrocarbon group which may optionally be substituted, and A is an amino acid residue or a peptide residue), preferably in the presence of a salt at a concentation exhibiting higher osmotic pressure than isotonic sodium chloride solution, and a medicine is found to promote absorption of the medicine through a gastrointestinal organ such as the colon and rectum, and through the vagina.
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patent: 3091569 (1963-05-01), Sheffner
patent: 3782971 (1974-01-01), Van Roon
patent: 3825664 (1974-07-01), Hagemann et al.
patent: 3904754 (1975-09-01), Morelle
patent: 4609640 (1986-09-01), Morishita et al.
Sawai-Chem. Abst.-vol. 97 (1982) p. 44324r.
De Mill-Chem. Abst., vol. 92 (1980) p. 28585t.
Eberhardt et al-Chem. Abst., vol. 88 (1978), p. 197670q.
Aikawa Renji
Katsuragi Shigeo
Morishita Masataka
Sugimoto Kenichi
Yamamoto Yoshiaki
Rosen Sam
Toyo Jozo company, Ltd.
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