Supports for oligomer synthesis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S431000, C548S435000

Reexamination Certificate

active

07576119

ABSTRACT:
Universal linkers, their facile processes of manufacture and methods of using the same are provided.

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Azhayev, A. V., “A New Universal Solid Support for Oligonucleotide Synthesis,”Tetrahedron(1999) 55(3):787-800.
Azhayev, A. V. et al., “Amide group assisted 3′-dephosphorylation of oligonucleotides synthesized on universal A-supports,”Tetrahedron(2001) 57(23):4977-4986.
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Lyttle, M. H. et al., “A Phosphate Bound Universal Linker for DNA Synthesis,”Nucleosides Nucleotides(1999) 18(8):1809-1824.
Maynard, H. D. et al., “Synthesis of Norbornenyl Polymers with Bioactive Oligopeptides by Ring-Opening Metathesis Polymerization,”Macromolecules(2000) 33:6239-6248.
McCluskey, A. et al., “The First Two Cantharidin Analgoues Displaying PP1 Selectivity,”Bioorg. Med. Chem. Lett. (2002) 12:391-393.
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Reg. No. 41532-47-2 “Isobenzofuran-4,7-imine-1,3-dione,3a,4,7,7a-tetrahydro-8-methyl-(9CI),”SciFinder, Aug. 29, 2002 2 pages (abstract only).
Reg. No. 99237-90-8 “Isobenzofuran-4,7-imine-1,3-dione, 8 acetyl-3a,4,7,7a-tetrahydro-, (3aα,4a,7a,7aα)-(9CI),”SciFinder, Aug. 29, 2002, 2 pages (abstract only).

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