Supports for oligomer synthesis

Details Supports for oligomer synthesis Supports for oligomer synthesis

2007-04-10

2007-04-10

McKane, Joseph K. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S431000, C548S435000

Reexamination Certificate

active

10989197

ABSTRACT:
Universal linkers, their facile processes of manufacture and methods of using the same are provided.

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Azhayev, A. V., “A New Universal Solid Support For Oligonucleotide Synthesis,”Tetrahedron55(3): 787-800, (1999).
Azhayev, A. V. et al., “Amide group assisted 3′-dephosphorylation of oligonucleotides synthesized on universal A-supports,”Tetrahedron(2001) 57(23): 4977-4986.
Crea, R. et al., “Synthesis of oligonucleotides on cellulose by a phosphotriester method,”Nucleic Acids Res.(1980) 8(10): 2331-2348.
Lyttle, M. H. et al., “A new universal linker for solid phase DNA synthesis,”Nucleic Acids Res.(1996) 24(14): 2793-2798.
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McCluskey, A. et al., “The First Two Cantharidin Analogues Displaying PP1 Selectivity,”Bioorg. Med. Chem. Lett.(2002) 12: 391-393.
Nelson, P. S. et al., “3′-Terminal Modification of Oligonucleotides Using a Universal Solid Support,”Nucleosides Nucleotides(1997) 16(10&11): 1951-1959.
Nelson, P. S. et al., “Rainbow™ Universal CPG: A Versatile Solid Support for Oligonucleotide Synthesis,”BioTechniques(1997) 22: 752-756.
Scheuer-Larsen, C. et al., “Introduction of a Universal Solid Support for Oligonucleotide Synthesis,”Nucleosides Nucleotides(1997) 16(1&2): 67-80.
Schwartz, M. E. et al., “A Universal Adapter for Chemical Synthesis of DNA or RNA on any Single Type of Solid Support,”Tetrahedron Lett.(1995) 36(1): 27-30.
Scott, S. et al., “A Universal Suport for Oligonucleotide Synthesis,”Innovation and Perspectives in Solid Phase Synthesis, Epton, R. (ed.) (1994), pp. 115-124.
Reg. No. 41532-47-2 “Isobenzofuran-4,7-imine-1,3-dione,3a,4,7,7a-tetrahydro-8-methyl-(9CI),”SciFinder, Aug. 29, 2002 2 pages (abstract only).
Reg. No. 99237-90-8 “Isobenzofuran-4,7-imine-1,3-dione, 8 acetyl-3a,4,7,7a-tetrahydro-, (3aα,4a,7a,7aα)-(9CI),”SciFinder, Aug. 29, 2002, 2 pages (abstract only).

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