Supports and their use

Details Supports and their use Supports and their use

1986-06-26

1989-03-14

Foelak, Morton

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

525 542, 5253266, 5253277, 5253275, 530334, 536 24, 536 25, 536 26, 536 27, 536 28, 536 29, 536121, 252 6254, 252 6256, 556419, 556420, 556421, 556422, 564 79, 564 80, 564 82, 564 89, C12P 1834, C12P 1838

Patent

active

048125121

ABSTRACT:
Novel supports useful in solid phase synthesis of oligonucleotides of the formula ##STR1## wherein .circle.P is a material selected from the group consisting of functionalized glass micropellets, silica functionalized by aminoalkyl trialkoxysilane capable of to obtain for ##STR2## Kieselguhr, polytetrafluoroethylene, cellulose and metallic oxides, m is an integer from 1 to 20, A is selected from the group consisting of alkyl of 1 to 20 carbon atoms, saturated cycloalkyl of 3 to 12 carbon atoms, phenyl and 5 to 6 member heterocycles, x and y are an integer from 0 to 20, x.sub.1 is an integer from 1 to 20 and y.sub.1 is an integer from 0 to 10, a process for the preparation of said supports, the use of said supports and intermediates.

REFERENCES:
patent: 4591614 (1986-05-01), Miller et al.
patent: 4638032 (1987-01-01), Benner
patent: 4659774 (1987-04-01), Webb et al.

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