Supported receptor and use thereof in an assay

Details Supported receptor and use thereof in an assay Supported receptor and use thereof in an assay

1978-09-27

1981-07-14

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, 422 57, 422 59, 422 61, 424 12, G01N 3348, G01T 100

Patent

active

042786517

ABSTRACT:
A supported receptor for use in an assay for a ligand in which the solid support includes a water insoluble polymer including at least one functional group which is either carboxyl, isothiocyanate, N-hydroxysuccinimide, imidazolide, bromoacetyl, maleimide, or diazomethylene, with the receptor being covalently linked to the support through the functional group. The preferred support is a particulate support including an impervious non-porous core and an outer porous coating having the water insoluble polymer, including the aforesaid functional groups, adhering thereto.

REFERENCES:
patent: 4059685 (1977-11-01), Johnson
patent: 4108975 (1978-08-01), Hales
patent: 4166102 (1979-08-01), Johnson
patent: 4217338 (1980-08-01), Quash
Am. Rev. Biochem. vol. 35, part II, pp. 875, 876, 878.

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