Supported liquid membrane delivery devices

Details Supported liquid membrane delivery devices Supported liquid membrane delivery devices

1995-05-23

1997-02-18

Spear, James M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424451, 424463, 424475, 424480, 424482, 424489, 424494, 424497, 424468, 5147723, 514773, 514784, 514785, A61K 930, A61K 932, A61K 936, A61K 922

Patent

active

056039530

ABSTRACT:
Supported liquid membrane delivery devices that release a beneficial agent to an aqueous environment following exposure to an environmental trigger. A microporous hydrophobic support membrane at least partially surrounds a beneficial agent- containing hydrophilic formulation. A hydrophobic liquid is held within the microporous support membrane by capillarity and the hydrophobic liquid is substantially permeable to the aqueous environment and the beneficial agent-containing hydrophilic formulation. The entrained hydrophobic liquid becomes substantially permeable to the aqueous environment upon exposure to an environmental trigger such as an enzyme, and the beneficial agent is subsequently released.

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