Supported aldehydic silanes and method of manufacture

Details Supported aldehydic silanes and method of manufacture Supported aldehydic silanes and method of manufacture

2006-05-16

2006-05-16

Ceperley, Mary E. (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

C435S007920, C436S525000, C436S526000, C436S529000, C436S531000, C530S391100, C530S410000

Reexamination Certificate

active

07045365

ABSTRACT:
A method for producing a derivatized aldehydic support matrix material includes activating surface hydroxyl groups on the support matrix material and reacting the activated hydroxyl groups with an aldehydic alkoxy silane. The derivatized aldehydic support matrix material produced is useful for immobilizing bio-molecules in biological applications.

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Bruning, C., et al.Aldehyde-functionalized Ethozysilanes as a New Enzyme Immobilization Reagents.J. Chem Soc., Chem Commun. 1995, pp. 2323-2324, especially Fig. 1and p. 2323, first through third full paragraphs.
Borchert, A., et al.High-Performance Liquid Affinity Chromatography on Silica-Bound Concanavalin A.Journal of Chromatography. 1982, vol. 244, pp. 49-56, Fig. 1.

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