Support matrix and immobilized enzyme system

Details Support matrix and immobilized enzyme system Support matrix and immobilized enzyme system

1982-11-08

1985-06-25

Naff, David M.

Chemistry: molecular biology and microbiology

Carrier-bound or immobilized enzyme or microbial cell;...

Enzyme or microbial cell is immobilized on or in an...

435177, 435180, 502 7, C12N 1114, C12N 1102, C12N 1108

Patent

active

045254567

ABSTRACT:
A support matrix which immobilizes enzymes by ion exchange forces comprises a core support deposited on which is a functionalized polyethylenimine insoluble in water. Such support matrices may be prepared from a virtually limitless variety of core supports since the functionalized polyethylenimines of this invention show excellent adhesive properties even to smooth surfaces. Such support matrices are particularly useful where the enzyme to be immobilized has a rather limited inherent half-life. The functionalized polyethylenimine is a carboxylic acid amide of polyethylenimine, a sulfonic acid amide of polyethylenimine or polyalkylated polyethylenimine.

REFERENCES:
patent: 4006059 (1977-02-01), Butler
patent: 4141857 (1979-02-01), Levy et al.
patent: 4235973 (1980-11-01), Tschang et al.
patent: 4434228 (1984-02-01), Swann

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