Support matrices for immobilized enzymes

Details Support matrices for immobilized enzymes Support matrices for immobilized enzymes

1979-11-16

1981-05-19

Konopka, P. E.

Compositions

Preservative agents

Anti-oxidants or chemical change inhibitants

435176, 435180, B01J 3106, C12N 1114, C12N 1108

Patent

active

042684234

ABSTRACT:
An improved method of preparing support matrices for immobilization of reactive chemical entities, such as enzymes, comprises deposition of a polyamine on a core support, such as an inorganic oxide, contacting the polyamine-coated core support with a bifunctional reagent which cross-links the polyamine and provides pendant functional groups, and recovering the matrix, wherein the improvement comprises deposition of the polyamine as a thin, uniform film from solvents of low surface tension.

REFERENCES:
patent: 4066504 (1978-01-01), Krasnobajew et al.
patent: 4141857 (1979-02-01), Levy et al.
patent: 4184986 (1980-01-01), Krasnobajew et al.

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