Electricity: measuring and testing – Particle precession resonance – Spectrometer components
Reexamination Certificate
2005-12-13
2005-12-13
Fulton, Christopher W. (Department: 2859)
Electricity: measuring and testing
Particle precession resonance
Spectrometer components
Reexamination Certificate
active
06975118
ABSTRACT:
It is possible to grasp the behavior of a protein in a cell by realizing a nuclear magnetic resonance imaging method having spatial resolutions on the scale of a cell, and to provide an industrial measure for developing a high-quality protein utilizing this technology. In order to realize spatial resolutions in the order of one-tenth the size of a cell, a supersensitive measurement is realized by the combination of a solenoid detector coil and a high magnetic field NMR of not less than 14 Tesla, which has not been used so far. It is combined with the magnetic field uniformity of 0.001 ppm, so that the supersensitive NMR imaging of 0.5 μm, which has been impossible heretofore, is realized. The physico-chemical behavior of protein molecules can be easily clarified, and thus the bioinfomatic network or the process of metabolism of the cell can be brought out.
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Aihara Katsuzou
Kakugawa Shigeru
Morita Hiroshi
Okada Michiya
Wakuda Tsuyoshi
Antonelli, Terry Stout and Kraus, LLP.
Fulton Christopher W.
Hitachi , Ltd.
Vargas Dixomara
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