Superoxide dismutase, its immobilized form, and their production

Details Superoxide dismutase, its immobilized form, and their production Superoxide dismutase, its immobilized form, and their production

1984-10-01

1986-01-07

Shapiro, Lionel M.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

435189, 435179, 435880, 435881, A61K 3750, C12N 902, C12N 1112, C12R 143

Patent

active

045633495

ABSTRACT:
A novel superoxide dismutase is produced by cultivating a microorganism belonging to the genus Serratia. The superoxide dismutase is useful as an antiinflammatory agent.
An immobilized superoxide dismutase has properties of decreased antigenicity and increased antiinflammatory activity.

REFERENCES:
The Journal of Biological Chemistry, vol. 245, No. 22, pp. 6176-6181 (1970).
Journal of Molecular Biology, vol. 105, pp. 333-335 (1976).
Superoxide and Superoxide Dismutase, pp. 517-536 (1977) (see p. 518, lines 28-35) Academic Press.
Current Microbiology, vol. 1, No. 6, 1978, pp. 371-376.
Journal of Bacteriology, vol. 134, No. 1, Apr. 1978, pp. 229-236.
Proceedings of the National Academy of Sciences of the U.S. of A., vol. 77, No. 2, pp. 1159-1163 (Feb. 1980).
Advances in Inflammation Research, vol. 1, pp. 273-280 (1979).
Journal of General Applied Microbiology, vol. 22, pp. 161-164.

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