Superoxide dismutase and process for production

Details Superoxide dismutase and process for production Superoxide dismutase and process for production

1975-05-06

1976-12-14

Shapiro, Lionel M.

Textiles: fiber preparation

195 66R, 195 65, C07G 7026

Patent

active

039974022

ABSTRACT:
The invention relates to a process for the production of superoxide dismutase and the superoxide dismutase so obtained. The superoxide dismutase obtained is extracted from marine bacterial strains and is characterized in that it comprises non-hematinic iron or copper and zinc, it has a molecular weight of about 33,000 to 40,000 .+-. 2500 and a pHi or isoelectric point of about 4 to 8.2 and it has maximum enzyme activity at a pH of about 8.5 to 10 with an optimum at about 9 to 9.5 and the use of said superoxide dismutases for the protection of oxidizable systems from auto-oxidation.

REFERENCES:
patent: 3920521 (1975-11-01), Michelson et al.
Keele Jr., et al., Journal of Biological Chemistry vol. 245 No. 22 pp. 6176-6180 (1970).
Forman et al., Archieves Biochemistry & Biophysics vol. 158 pp. 396-400 (1973).
King et al., editors; Oxidases and Related Redox Systems, vol. 1 pp. 51-76 (Paper by McCord et al., "Superoxide and Superoxide Dismutase" 1973.

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