Super-antigen fusion proteins and the use thereof

Details Super-antigen fusion proteins and the use thereof Super-antigen fusion proteins and the use thereof

2005-07-19

2009-11-17

Leavitt, Maria (Department: 1633)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

C424S186100, C424S192100, C424S194100, C424S221100, C530S300000, C530S323000

Reexamination Certificate

active

07618635

ABSTRACT:
The present invention relates to a super-antigen fusion protein, comprising: a peptide fragment whose sequence corresponds to a partial SARS E2 spike protein; and a translocating peptide fragment for transporting a protein into a cell and translocating the protein in cytosol; wherein, the amino acid sequence of the peptide fragment corresponding to the partial SARS E2 spike protein includes SEQ ID NO. 1, SEQ ID NO. 2, SEQ ID NO. 3 or SEQ ID NO. 4. The present invention further relates to DNA sequences corresponding to the partial SARS E2 spike protein includes SEQ ID NO. 5, SEQ ID NO. 6, SEQ ID NO. 7, or SEQ ID NO. 8; wherein the DNA sequences are able to express specific proteins in anE. Coliexpression system.

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