.sup.13 CO.sub.2 Breath test

Chemistry: physical processes – Physical processes – Crystallization

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23232R, G01N 3352

Patent

active

042983479

ABSTRACT:
A method for the analysis of exhaled carbon dioxide for clinical diagnostic application which contains a mixture of .sup.13 CO.sub.2 and .sup.12 CO.sub.2 is disclosed. The method includes the use of a solution which absorbs the carbon dioxide from the exhaled air, reacts with the carbon dioxide to form a ketone and uses the height of the unique infrared spectral peaks in the carbonyl frequency range to quantitate the .sup.13 CO.sub.2 and the .sup.12 CO.sub.2 components of the exhaled air.

REFERENCES:
patent: 3208827 (1965-09-01), Borkenstein
patent: 3725701 (1973-04-01), Link
patent: 3837807 (1974-09-01), Tarkkanen
patent: 4027972 (1977-06-01), Davies
Hirano et al., Analytical Biochemistry 96, 64-69 (1979).
Volpin et al., "The Reactions of Organometallic Compounds with Carbon Dioxide", Institute of Organo-Element Compounds, Academy of Science of the USSR, Moscow, USSR, pp. 313-386.
Helge et al., Chemical Abstracts, vol. 90, 1979, No. 90: 37276d.

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