.sup.123m Te-Labeled biochemicals and method of preparation

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424 1, C07J 900

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042150450

ABSTRACT:
A novel class of .sup.123m Te-labeled steroids and amino acids is provided by the method of reacting a .sup.123m Te symmetric diorgano ditelluride with a hydride reducing agent and a source of alkali metal ions to form an alkali metal organo telluride. The alkali metal organo telluride is reacted with a primary halogenated steroidal side chain, amino acid, or amino acid precursor such as hydantoin. The novel compounds are useful as biological tracers and as organal imaging agents.

REFERENCES:
patent: 4041145 (1977-08-01), van der Veek
Basmadjian et al., Jour. of Nuclear Medicine, vol. 19, No. 6, pp. 689, 718.
Knapp; F. F. et al., "Journal of Nucl. Med.", vol. 18, No. 6, pp. 600 and 610, Jun. 1977.

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