Sulpinine, secopenitrem B and aflatrem B antiinsectan metabolite

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514183, 540462, 548417, A01N 4390, C07D20994

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active

051303264

ABSTRACT:
Indole compounds named "sulphinine" and "secopenitrem" have been isolated from the sclerotia of from fungi Aspergillus sulphureus. An indole compound named "aflatrem B" has been isolated from the sclerotia of the fungi Aspergillus flavus. The compounds are effective for controlling Coleopteran and Lepidopteran insects.

REFERENCES:
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patent: 5017598 (1991-05-01), Dowd et al.
de Jesus et al., "Tremorgenic Mycotoxins from Penicillin crustosum", J. Chem. Soc. Perkin Trans I, (1983), pp. 1857-1861.
Gallagher, R. T. and Clardy, J., "Aflatrem, A Tremorgenic Toxin from Aspergillus flavus", Tetrahedron Lett., vol. 21, (1980), pp. 239-242.
Springer, J. P. and Clardy, J., "Paspaline and Paspalicine, Two Indole--Mevalonate Metabolites from Claviceps Paspali", Tetrahedron Lett., vol. 21, (1980), pp. 231-234.
Gallagher et al., "Paspalinine, A Tremogenic Metabolite from Claviceps paspali Stevens Et Hall", Tetrahedron Lett., vol. 21, (1980), pp. 235-238.

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