Sulphones which modulate the action of gamma secretase

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Sulfur – selenium or tellurium compound

Reexamination Certificate

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C568S034000

Reexamination Certificate

active

07411004

ABSTRACT:
Disclosed are sulphones which modulate the action of gamma-secretase. The compounds are useful in the treatment or prevention of Alzheimer's disease.

REFERENCES:
patent: 3016403 (1962-01-01), Dodson
patent: 4379921 (1983-04-01), Funaki et al.
patent: 5703129 (1997-12-01), Felsenstein et al.
patent: 6013649 (2000-01-01), Freskos et al.
patent: 56-026847 (1981-03-01), None
patent: 8-53408 (1996-02-01), None
patent: WO 9803164 (1998-01-01), None
patent: WO 00/50391 (2000-08-01), None
patent: WO 03/055850 (2003-07-01), None
patent: WO 03/059335 (2003-07-01), None
Database CAS Online on STN, Chem. Abstr., Accession No. 1908:3476, Posner, Contribution to our Knowledge of the Unsaturated Compounds. V. Addition of Mercaptans to Unsaturated Acids, Ber. (1908), 40, 4788-94, abstract only.
Database CAS Online on STN, Chem. Abstr., Accession No. 1951: 41283, Balfe et al., Alkyll-oxygen fission in carboxylic esters. VII. Hydrolysis of methyl-2-naphthylcarbinyl hydrogen phthalate, Journal of the Chemical Society (1951) 380-1, abstract only.
CAS Registry No. 329904-86-1 Indexed in STN Registry on Apr. 4, 2001.
CAS Registry No. 95137-18-1 Indexed in STN Registry on Mar. 9, 1985.
CAS Registry No. 94863-97-5 Indexed in STN Registry on Feb. 17, 1985.
Jonczyk et al. Chemistry Letters, pp. 1557-1560, 1983.
Marcantoni et al. Journal of Organic Chemistry (1998), 63(11), 3624-3630.
Obushak et al., Russian Journal of General Chemistry (1997), 67(8), 1317.
Fournier et al. European Journal of Medicinal Chemistry (1982), 17(1), 53-8.
Julia et al., Bulletin de la Societe Chimique de France (1976), (3-4, Pt. 2), 513-18.
Julie et al., Bulletin de la Societ Chimique de France (1976), (11-12, Pt. 2), 1941-6.
Redman et al., Journal of the Chemical Societ, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) (1978), (11), 1135-44.
Pascali et al. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (197201999) (1973), (11), 1166-8.
Yamamot et al. Bulletin of the Chemical Society of Japan (1987), 60(4), 1523-4.
Marczak et al. Synthetic Communications (1990), 20(10), 1511-20.
Messinger, P. Archiv der Pharmazie (1973), 306(6), 458-62.
Chang et al. Journal of Organic Chemistry (1978), 43(2), 373-4.
Vidal et al. Tetrahedron Letters (1986), 27(32), 3733-6.
M. Makosza et al., “Ambiphilic Reactivity of 2,4-Dinitrobenzylp-Tolyl Sulfone Carbanion”, Polish. J. Chem., vol. 72, pp. 1198-1201 (1998).

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