Sulphonamido containing phenylalkanoic acids as thromboxane A.su

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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514539, 514603, 514604, 560 12, 562430, 564 91, A61K 3119, A61K 31235, A61K 3118

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active

052800431

ABSTRACT:
Phenylalkanoic acids containing a sulphonamido group, and their use in a method of treatment of thromboxane-A.sub.2 mediated diseases are disclosed. A compound of the invention is 4-[4-(phenyl-sulphonamido)phenyl]butyric acid.

REFERENCES:
patent: 4258058 (1981-03-01), Witte et al.
patent: 4443477 (1984-04-01), Witte et al.
Chemical Abstracts, vol. 105, No. 11, 97029p, (1986).
Coutts et al., J. Chem. Soc. Perkin Trans. 1, pp. 1829-1836, (1985).

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