Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-10-15
1998-11-17
Ford, John M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5142278, 5142282, 5142285, 5142358, 5142365, 5142322, 5142325, 5142348, 5142345, 514252, 514249, 514259, 514262, 514261, 514269, 544319, 544238, 544295, 544296, 544122, 544123, 544 82, 544 586, 544265, 544276, 544277, 544284, C07D23969, C07D40112, C07D40312, A61K 31505
Patent
active
058377085
ABSTRACT:
Compounds of the formula ##STR1## wherein the variables are hereinbelow defined. The compounds of formula I are inhibitors for endothelin receptors. They can be used for the treatment of disorders which are associated with endothelin activities, especially circulatory disorders such as hypertension, ischaemia, vasospasms and angina pectoris.
REFERENCES:
patent: 5292740 (1994-03-01), Burri et al.
Burri et al., Chemical Abstract, vol. 120 (entry 217711) Apr. 25, 1994.
Breu Volker
Burri Kaspar
Cassal Jean-Marie
Clozel Martine
Hirth Georges
Epstein William H.
Ford John M.
Hoffmann-La Roche Inc.
Johnston George W.
Parise John P.
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