Sulphated vinyl polymer in composition for treating retroviral i

Details Sulphated vinyl polymer in composition for treating retroviral i Sulphated vinyl polymer in composition for treating retroviral i

1992-01-15

1994-03-08

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

424 7817, 514885, A61K 4734

Patent

active

052925056

ABSTRACT:
Sulphated vinyl polymers such as sulphated polyvinylalcohol, sulphated copolymers of (meth)acrylic acid and vinylalcohol, and pharmaceutically acceptable salts thereof, have an antiviral effect against human immunodeficiency virus and may therefore be used as a therapeutic agent for treating retrovirus infections like AIDS and AIDS-related diseases. Their antiviral activity is apparently based on inhibition of virus adsorption; their inhibitory effect on giant cell formation is stronger than that of dextran sulphate.

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Chemical Abstracts "Antiviral activity of some synthetic polymers and prospects for their use in practical medicine."

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