Sulphated K5 antigen and sulphated K5 antigen fragments

Details Sulphated K5 antigen and sulphated K5 antigen fragments Sulphated K5 antigen and sulphated K5 antigen fragments

1989-03-08

1991-12-10

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424 88, 424 92, 514 54, 514 56, 514 62, 536 54, 536 551, C08B 3700, A61K 31715

Patent

active

050719696

ABSTRACT:
The invention relates to sulphated K5 antigen and sulphated K5 antigen fragments containing at least 3 monosaccharide units and salts thereof, having interesting antiangiogenic and antitumor activities and a favorable ratio of the activities with respect to anticoagulant properties. In addition, the compounds can be used for the treatment of diseases caused by envelope viruses.

REFERENCES:
patent: 4438108 (1984-03-01), Sanders et al.
patent: 4510132 (1985-04-01), Vaara
patent: 4719202 (1988-01-01), van Boeckel et al.
patent: 4816390 (1989-03-01), Kondo et al.
patent: 4841041 (1989-06-01), van Boeckel et al.
J. Riesenfeld et al., "Biosynthesis of Heparin", Glyconjugate Journal, vol. 4, pp. 179-189 (1987).

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