Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...
Reexamination Certificate
2008-03-18
2008-03-18
Sergent, Rabon (Department: 1711)
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
Mixing of two or more solid polymers; mixing of solid...
C424S078170, C424S078370, C514S054000, C527S300000, C527S301000, C528S049000, C528S071000, C536S122000, C536S123100, C536S126000
Reexamination Certificate
active
07345117
ABSTRACT:
The present invention relates to the synthesis of a haemocompatible polymer, consisting of a polyurethane bound covalently to sulphated hyaluronic acid. These sulfated derivatives have anticoagulative, non-thrombogenic, antiviral and anti-inflammatory properties. They also have the ability to inhibit platelet adhesion, aggregation and activation. The invention is particularly advantageous in resisting the enzyme hyaluronidase, therefore ensuring anti-coagulant activities for longer periods of time when compared to similar compounds. This biocompatible polymer material is well suited for surgical or other medicinal uses.
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Biomaterials, vol. 18 No. 21, Pub. 1997, pp. 1411-1415, “Biocompatibility and Enzymatic Degadation Studies on Sulphated Hyaluronic Acid Derivatives”, by Giovanni Abatangelo, Rolando Barbucci, Paola Brun and Stefania Lamponi.
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Barbucci Rolando
Callegaro Lanfranco
Consumi Marco
Magnani Agnese
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