Sulfooxy-pyrimidinium, -pyridinium, and -triazinium hydroxide in

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

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544113, 544 586, 544131, 544196, 544197, 544198, 544199, 544205, 544206, 544207, 544295, 544323, 544324, 544327, 544360, 546193, 546257, 546275, 546281, 546307, 2602433, 2602444, 424246, 4242485, 424249, 424250, 424251, 424263, C07D21389, C07D23948, C07D25118, C07D41304

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042873380

ABSTRACT:
The present invention provides novel substituted sulfooxy-pyrimidinium, -pyridinium, and -triazinium hydroxide inner salts. These compounds are useful for the treatment of hypertension and peripheral vascular diseases. They are formed by reacting the corresponding aminopyrimidine, aminotriazine, and aminopyridine N-oxides with a latent sulfate source such as pyridinium-sulfur trioxide complex, triethylamine-sulfur trioxide complex, chlorosulfonic acid or chlorosulfuryl chloride.

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patent: 3461461 (1969-08-01), Anthony et al.
patent: 3464987 (1969-09-01), Ursprung et al.
patent: 3973016 (1976-08-01), Morrison et al.
patent: 4021562 (1977-05-01), Lawson et al.
patent: 4080500 (1978-03-01), Lawson et al.

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