Sulfonyl urea and carbamate ACAT inhibitors

Details Sulfonyl urea and carbamate ACAT inhibitors Sulfonyl urea and carbamate ACAT inhibitors

1993-07-01

1999-11-09

Kumar, Shailendra

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514520, 514529, 514562, 514593, 558417, 560103, 560110, 562433, 564 39, 564 42, A61K 31175, C07C31155

Patent

active

059815957

ABSTRACT:
A pharmaceutically useful compound which lowers blood cholesterol levels having the formula ##STR1## wherein X is oxygen or --NH--; Ar is phenyl, substituted phenyl, naphthyl or substituted naphthyl; R.sub.1 is hydrogen, lower alkyl or benzyl; and R.sub.2 is a straight or branched alkyl group having from 5 to 17 carbon atoms which may be substituted on the 1-carbon position with methyl, ethyl, phenyl, or substituted phenyl, or a cycloalkyl group having from 3 to 8 carbon atoms.

REFERENCES:
patent: 3013072 (1961-12-01), McLamore
patent: 3983107 (1976-09-01), Holland
patent: 4845128 (1989-07-01), Harper et al.
patent: 5254589 (1993-10-01), Picard
Chemical Abstracts, vol. 60, No. 3, Feb. 3, 1964, Columbus, Ohio, US; A. Brazzi `Color couplers.` column 3143B ; see abstract & GB, A, 909 318 (Ferrania Societa Per Azioni) Oct. 31, 1962.

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