Sulfonyl group containing compounds and their use for the...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S252200, C514S252120, C514S254020, C514S254100, C514S256000, C514S317000, C514S321000, C514S323000, C514S326000, C514S329000, C514S330000, C514S331000, C544S295000, C544S376000, C544S377000, C544S335000, C544S382000, C544S383000, C544S368000, C544S379000, C546S196000, C546S197000, C546S209000, C546S214000, C546S223000, C546S225000, C546S236000

Reexamination Certificate

active

07084144

ABSTRACT:
A compound having the general formula (I):wherein: X is N or C; R0is H, a lower alkyl group, a lower O-alkyl group,lower alkyl group, a benzyl group, a phenyl group, a heterocyclic amine group, a cycloalkyl group, a cycloalkyl group substituted with O-alkyl or, a furyl group;R1and R2are, independently, H, an amine group, a lower alkyl group, a lower O-alkyl group, a lower S-alkyl group or a lower N-alkyl group, or R1and R2taken together with the carbon atoms to which they are attached form a five-membered carbocyclic or heterocyclic ring, where the heteroatoms of the heterocyclic ring are one or two oxygen atoms, and/or where any substituent on said carbocyclic or heterocyclic ring is chosen from O, S and N; n is 0,1,2,3 or 4;m is 0 or 1; and pharmaceutically acceptable salts thereof;with the proviso that said compound is not 1-[(4-methoxyphenyl)sulfonyl]piperazine or 1-(1,3-benzodioxol-5-ylsulfonyl)piperazine. The compounds are useful as active ingredients in pharmaceutical compositions and as a medicament for the treatment of erectile dysfunction.

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