Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2011-03-29
2011-03-29
Loewe, Sun Jae Y (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S412000, C514S618000, C564S188000, C540S581000
Reexamination Certificate
active
07915252
ABSTRACT:
Sulfonyl derivatives of structural formula I are selective inhibitors of the 11β-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome or Syndrome X, and other symptoms associated with NIDDM.
REFERENCES:
patent: 6849636 (2005-02-01), Waddell et al.
patent: WO 2004/089470 (2004-10-01), None
Adamantane, http://en.wikipedia.org/wiki/Adamantane.
Chawla et al., “Challenges in Polymorphism of Pharmaceuticals”, CRIPS vol. 5, No. 1, Jan.-Mar. 2004 (**4 Pages**.
Newman et al., “Solid-state analysis of the active pharmaceutical ingredient in drug products”, DDT vol. 8, No. 19, Oct. 2003, p. 898-905.
Treatment, http://www.ncbi.nlm.nih.gov/pubmed/12960099.
Treatment2, http://www.ncbi.nlm.nih.gov/pubmed/12519867.
Treatment3, http://jem.rupress.org/cgi/content/abstract/202/4/517.
Grob et al., caplus an 1978:579314.
Supplementary European Search Report, dated Jun. 17, 2009, Application No. EP 05 77 7427, corresponding to PCT/US05/027500.
Balkovec James M.
Gu Xin
Leeman Aaron H.
Maletic Milana
Santorelli Gina M.
Daniel Mark R.
Loewe Sun Jae Y
Merck Sharp & Dohme
Parr Richard S.
Struse Heidi
LandOfFree
Sulfonyl compounds as inhibitors of 11-beta-hydroxysteroid... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Sulfonyl compounds as inhibitors of 11-beta-hydroxysteroid..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sulfonyl compounds as inhibitors of 11-beta-hydroxysteroid... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2765112