Sulfonium salts of pyrrolylbenzimidazoles

Details Sulfonium salts of pyrrolylbenzimidazoles Sulfonium salts of pyrrolylbenzimidazoles

1996-11-25

1998-09-15

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514394, C07D40302, A61K 31415

Patent

active

058080872

ABSTRACT:
Compounds of formula (1): ##STR1## wherein m is an integer 1, 2 or 3,

REFERENCES:
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patent: 3325506 (1967-06-01), Jones et al.
patent: 5273991 (1993-12-01), Lee
Arcamone et al, "Synthesis, DNA-Binding Properties, and Antitumor Activity of Novel Distamycin Derivatives", J. Med. Chem., 1989, 32, pp. 774-778.
Alley et al, "Feasibility of Drug Screening with Panels of Human Tumor Cell Lines Using a Microculture Tetrazolium Assay", Cancer Research, 1988, 48, pp. 589-601.
Arcamone et al, "Structure and Synthesis of Distamycin A", Nature, 1964, vol. 203, pp. 1064-1065.
Baker et al, "Sequence-Specific Cleavage of Double-Helical DNA. N-Bromoacetyldistamycin", J. Am. Chem. Soc., 1985, 107, pp. 8266-6268.

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