Sulfonated xanthene derivatives

Chemistry: analytical and immunological testing – Involving producing or treating antigen or hapten – Producing labeled antigens

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435 6, 435 721, 435 737, 436529, 436531, 436800, 436837, 436829, 5303913, 5303915, 530402, 544 70, 544 79, 544129, 544130, 544141, 544231, 544260, 544364, 544372, 544375, 546 18, 546 37, 546 41, 546 48, 546 62, 546187, 548407, 548418, 548426, 548525, 549 14, 549 33, 549 40, 549223, 549225, 549226, 549227, G01N 33533, G01N 33554, C07K 1612, C07K 1618, C07D31182

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active

061301019

ABSTRACT:
The present invention describes xanthene dyes, including rhodamines, rhodols and fluoresceins that are substituted one or more times by a sulfonic acid or a salt of a sulfonic acid. The dyes of the invention, including chemically reactive dyes and dye-conjugates are useful as fluorescent probes, particularly in biological samples.

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