Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2011-08-23
2011-08-23
Pryor, Alton N (Department: 1616)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S391500, C530S402000, C530S409000
Reexamination Certificate
active
08003767
ABSTRACT:
Fluorescent, sulfonated 3,7-diamino-[8,9]benzophenoxazine dyes are provided that are especially useful for labelling biopolymers and other substrates. The dye-labelled conjugates can be used in a variety of contexts, including cell surface assays employing intact, live cells and in nucleic acid detection methods. The new dyes are water soluble and can be conjugated to a variety of substrates, such as polynucleotides, nucleosides, nucleotides, peptides, proteins, antibodies, carbohydrates, ligands, particles and surfaces.
REFERENCES:
patent: 3655601 (1972-04-01), Ottawa et al.
patent: 4237281 (1980-12-01), Long
patent: 4714763 (1987-12-01), Theodoropulos
patent: 4841048 (1989-06-01), Sawamoto et al.
patent: 4962197 (1990-10-01), Foley et al.
patent: 5366860 (1994-11-01), Bergot et al.
patent: 5770716 (1998-06-01), Khan et al.
patent: 5792389 (1998-08-01), Hammond et al.
patent: 5936087 (1999-08-01), Benson et al.
patent: 1146941 (1983-05-01), None
patent: 0019198 (1980-11-01), None
patent: 62190258 (1987-08-01), None
patent: WO 97/29154 (1997-08-01), None
patent: WO 99/15517 (1999-04-01), None
patent: WO-0118124 (2001-03-01), None
patent: WO-0120334 (2001-03-01), None
patent: WO-0174968 (2001-10-01), None
Becker et al., “The Photosensitizers Benzophenoxazine and Thiazines: Comprehensive Investigation of Photophysical and Photochemical Properties,”Photochemistry and Photobiology51(5):533-538 (1990).
Briggs et al., “Synthesis of Functionalised Fluorescent Dyes and Their Coupling to Amines and Amino Acids,”J. Chem. Soc., Perkin-Trans. 1:1051-1058 (1997.
Cincotta et al., “Novel Red Absorbing Benzo[a]phenoxazinium and Benzo[a] phenothiazinium Photosensitizers: in vitro Evaluation,”Photochemistry and Photobiology46(5) 751-758 (1987).
VanAllan et al., “The Reaction of 12H-Benzo[a]phenothiazine and 12H-Benzo[b] phenoxazine with Certain Heterocyclic Azides,”J. Org. Chem. 34(6):1691-1694 (1969).
V. Stuzka et. al.: “Infrared Spectroscopy of Benzo(a)phenoxazines” Spectrochim. Acta, Part A (1967), vol. 23, No. 7, 1967, pp. 2175-2183.
V. Stuzka et. al.: “Oxazines as Acid-Base Indicators ; Some Meldola's Blue” Chemicke Zvesti (1968), vol. 22, No. 6, 1968, pp. 431-438.
Okafor C.O.: “Synthesis, Properties and Uses of Angular Phenoxazines” Dyes and Pigments, Elsevier Applied Science Publishers. Barking, GB, vol. 7, No. 2, 1986, pp. 103-131.
International Search Report from PCT/US 01/14110, Jan. 2002.
U.S. Appl. No. 10/267,551, “Amendment after Notice of Allowance”, Jun. 5, 2006.
U.S. Appl. No. 10/267,551, “Preliminary Amendment with RCE”, Aug. 17, 2006 , 7.
2,407,726, “CA Office Action”, Feb. 1, 2008, 2.
EP01932860.8, “EP Examination”, Dec. 13, 2007 , 3.
EP01932860.8, “EP Examination”, Jun. 27, 2006 , 3.
Yan Xiongwei
Yuan Pau Miau
Applied Biosystems LLC
Life Technologies Corporation
Pryor Alton N
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