Sulfonamidodioxepanes, methods of preparation, intermediates, sa

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514884, 549333, 549347, A01N 4332, C07D32100

Patent

active

056355297

ABSTRACT:
Novel O-substituted or O-unsubstituted 6-sulfonamido-1,3-dioxepane-5-ols having hypoglycemic activity are obtained from 6-amino-1,3-dioxepane-5-ol, tetrahydro-6H-[1,3]-dioxepino[5,6-d]oxazole, 5,6-epoxy-1,3-dioxepane or N-sulfonyl-tetrahydro-1H,4H-[1,3]-dioxepino[5,6-b]azirine as starting materials.

REFERENCES:
Chemical Abstract vol. 83 No. 164098 (1975) "Stereocontrolled route to a key intermediate for the synthesis of maytansine".

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