Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-12-21
1996-11-26
McKane, Joseph
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142315, 5142355, 5142372, 5142378, 5142385, 514252, 514255, 514315, 514318, 514326, 514331, 514333, 544111, 544132, 544160, 544405, 544408, 544407, 546193, 546194, 546231, 546233, 546247, A61K 31395, C07D41312
Patent
active
055785948
ABSTRACT:
Sulfonamidocarboxamides of the formula ##STR1## wherein A, M, Q, X and Y have the significance given in the description, as well as hydrates, solvates and salts thereof, which inhibit thrombin-induced blood platelet aggregation and clotting of fibrinogen in plasma, as described. The compounds of formula I can be prepared by amidination of a cyclic amino group standing for grouping X or by C(O)N(Q) amide formation.
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Ackermann Jean
Banner David
Gubernator Klaus
Hilpert Kurt
Schmid G erard
Hoffmann-La Roche Inc.
Johnston George W.
McKane Joseph
Silverman Robert A.
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