Sulfonamidocarboxamides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514331, 546231, 546247, A61K 31445, C07D21114

Patent

active

054058546

ABSTRACT:
Sulfonamidocarboxamides of the formula ##STR1## wherein A, M, Q, X and Y have the significance given in the description, as well as hydrates, solvates and salts thereof, which inhibit thrombin-induced blood platelet aggregation and clotting of fibrinogen in plasma, as described. The compounds of formula I can be prepared by amidination of a cyclic amino group standing for grouping X or by C(O)N(Q) amide formation.

REFERENCES:
patent: 4227006 (1980-10-01), Okamoto et al.
patent: 4258192 (1981-03-01), Okamoto et al.
patent: 4879313 (1989-11-01), Tjoeng et al.
patent: 5037808 (1991-08-01), Tjoeng et al.
patent: 5053393 (1991-10-01), Tjoeng et al.
patent: 5260307 (1993-11-01), Ackermann et al.
Drugs of the Future, 17, 1992, 1087-90.
J. Med. Chem. 33, 1990, 1406-1413, Kato et al.
Biochem. J. 55, 1955, 170-171, Dixon.
J. Heterocycl. Chem. 23, 1986 929-933, Grande et al.
J. Med. Chem. 1980, 23, 1293-1299, vol. 12, Kikumoto et al.
Pharmazie 39, 1984, 226-230, Wagner et al.
Thrombosis and Haemotasis 67, 1992, 56-59, Knabb et al.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Sulfonamidocarboxamides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Sulfonamidocarboxamides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sulfonamidocarboxamides will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1538733

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.