Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Reexamination Certificate
2008-01-01
2008-01-01
Andres, Janet L. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
C514S659000, C562S444000, C562S503000, C562S506000
Reexamination Certificate
active
11426482
ABSTRACT:
The present invention provideswherein R1is selected from the group consisting of C1-C10alkoxy, OH and NR4R5;R2is selected from the group consisting of C1-C10alkyl and (CH2)nOH;R3is selected from the group consisting of C1-C10alkyl, heteroaryl, e.g. thienyl, furanyl and pyridyl, phenyl, mono, -di-, tri-substituted phenyl and heteroaryl;R4and R5are independently selected from the group consisting of H, C1-C10alkyl, C1-C10alkyl hydroxyl;m is0or an integer from1to3andn is an integer of from1to4.These compounds are useful in lowering intraocular pressure and/or treating glaucoma or providing neuroprotection to the eye of a human patient.
REFERENCES:
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Starr, M.S.Exp. Eye Res. 1971, 11, pp. 170-177; Bito, L. Z.Biological Protection with ProstaglandinsCohen, M. M., ed., Boca Raton, Fla, CRC Press Inc., 1985, pp. 231-252.
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Allergan Inc.
Andres Janet L.
Baran Robert J.
Johnson Brent A.
Robinson Binta
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