Sulfonamide lactam inhibitors of FXa and method

Details Sulfonamide lactam inhibitors of FXa and method Sulfonamide lactam inhibitors of FXa and method

2007-01-23

2007-01-23

Jiang, Shaojia (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S349000, C514S326000, C546S207000, C546S218000

Reexamination Certificate

active

10374299

ABSTRACT:
Sulfonamide lactams of the following formulawherein X, R1, R2, R3, R4, R4a, R5, R5a, R6, R6a, R7and R8are as described herein, are provided which inhibitors of Factor Xa and are useful as anticoagulants in the treatment of cardiovascular diseases associated with thromboses.

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