Sulfonamide derivatives, intermediate thereof, its...

Details Sulfonamide derivatives, intermediate thereof, its... Sulfonamide derivatives, intermediate thereof, its...

2007-05-29

2007-05-29

Wilson, James O. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S254010, C514S255020, C540S575000, C544S372000, C544S383000

Reexamination Certificate

active

10475539

ABSTRACT:
The present invention relates to a novel sulfonamide derivatives and novel intermediates thereof, preparation thereof, and a pharmaceutical composition comprising the same, and more particularly, to novel sulfonamide derivatives and intermediates thereof that are used as angiogenesis controlling material and that can inhibit overexpression of matrix metalloproteinase that decomposes protein constituents in extracellular and basement membranes of connective tissues, and preparation methods thereof, and a pharmaceutical composition comprising the same.

REFERENCES:
patent: 5753653 (1998-05-01), Bender et al.
patent: WO 9633172 (1996-10-01), None
patent: WO 9827069 (1998-06-01), None
patent: WO-00/44709 (2000-08-01), None
patent: WO 0102371 (2001-01-01), None
J. Med. Chem., vol. 43, No. 3, pp. 369-380, 2000.
Levin et al., “The Synthesis and Biological Activity of a Novel Series of Diazepine MMP Inhibitors”, Bioorganic & Medicinal Chemistry Letters, pp. 2657-2662 (1998).

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